Applying for Access

Tiers of Data Access

The INCLUDE Data Hub hosts thousands of data files holding genetic information of individuals with Down syndrome. These files are protected under a two-tier system.

Registered access files are immediately available to any user who registers a Data Hub account. Once you agree to the Terms and Conditions of the Data Hub and log in you will be able to access these files for analysis.

Controlled access files are only available to users who have been specifically granted permission by the appropriate Data Access Committee (DAC). Any user can review these files on the Data Hub, but will only be able to access their contents for analysis if they have been approved.

Determining a File's Access Tier

The access tier of a file can be determined by reviewing it in the Data Exploration Tool. Registered tier files are labeled with an R while controlled tier files are labeled with a C. The permissions associated with the current user's accounts are represented with the lock symbols. A closed lock means the user does not have permission to access this file, while an opened lock does grant access.

For more details about the Data Exploration Tool, see our page which explores that tool in detail.

Accessing Genomic Data Authorized Through dbGaP

dbGaP (Database of Genotypes and Phenotypes) is an NIH platform that archives and distributes data from funded studies. Studies with genomic data on the INCLUDE Data Hub require dbGaP approval to access this source of controlled-tier data.

dbGaP provides their own directions for submitting a successful application.

• Tips for Preparing a Successful Data Access Request (pdf)
• NCBI Tutorial - dbGaP: Apply for Controlled Access Data (YouTube)

🚧

A Note About dbGap Authorizations

dbGaP applications are limited to an individual. Applicants can also request other downloaders can be authorized on a single application, for example other members of a laboratory. Be sure to use their eRA Commons ID in the application.

Users who are approved will have their access granted in the INCLUDE Data Hub automatically. Be sure to follow the directions on the Connecting Platforms page to ensure the Data Hub recognizes your approval.